Answer
Yes. Morphine metabolites can accumulate when renal function is reduced, increasing prolonged sedation and respiratory depression. Product selection and treatment require clinical review.
Sources for this answer
- Morphgesic SR 10mg Tablets — Current selected SmPCemc · Summary of Product Characteristics
- Actimorph 1 mg Orodispersible tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.