Answer
Fluconazole is not expected to reduce pill effectiveness, but vomiting or severe diarrhoea can impair oral contraceptive protection; follow the pill leaflet’s advice.
Sources for this answer
- Canesten Thrush Duo Oral Capsule & External Cream 150mg / 2% w/w capsule and cream — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.