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Medicines GlucarpidaseQuestion & answer

Glucarpidase · Medicine question

Does it remove methotrexate from inside cells?

iatroX medicinesPublished 17 August 2026Reviewed 17 August 2026

The answer

Answer

No. It acts mainly in plasma and does not readily cross cell membranes.

Sources for this answer

Voraxazeemc · SmPC Current selected SmPC · Version 1

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Glucarpidase

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More questions about Glucarpidase

Is glucarpidase chemotherapy?Does it replace folinic acid rescue?Can it reverse methotrexate-related kidney damage?Why are methotrexate levels checked afterwards?Why can immunoassay results be misleading?Can children receive glucarpidase?

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