dornase alfa · Medicine question

Does inhaled dornase alfa have low systemic absorption?

iatroX medicinesPublished 8 November 2026

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Yes, inhaled dornase alfa shows low systemic exposure in patients, with serum measurements during repeated dosing suggesting low systemic absorption or accumulation.

Sources for this answer

Pulmozyme 2500 U/ 2.5ml, nebuliser solutionRoche Products Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 12Document updated 26 April 2017

Sources checked 8 November 2026

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