Answer
Yes. It can increase warfarin's anticoagulant effect and bleeding risk, so clotting tests may need closer monitoring.
Sources for this answer
- Fluconazole 50 mg capsules — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.