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Medicines tezepelumabQuestion & answer

tezepelumab · Medicine question

Do theophylline and aminophylline affect tezepelumab clearance?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Theophylline and aminophylline had no effect on tezepelumab clearance based on population pharmacokinetic analysis.

Sources for this answer

Tezspire 210 mg solution for injection in pre-filled syringeAstraZeneca UK Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated 15 December 2025

Sources checked 8 November 2026

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tezepelumab

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