Clinical CPD topic
Chronic lymphocytic leukaemia: practise, reflect and record
Practise chronic lymphocytic leukaemia through five clinical cases, review the explanations and build a professional learning record. Recognise likely CLL and select flow cytometry for confirmation.
First published · Sources checked
What you’ll work on
- Recognise likely CLL and select flow cytometry for confirmation.
- Identify when an atypical B-cell phenotype requires exclusion of mantle-cell lymphoma.
- Distinguish CLL suitable for active monitoring from disease requiring treatment because of progressive marrow-failure anaemia.
Think through a clinical case
Decide how you would approach this case before opening the question session.
A 65-year-old with fatigue, night sweats, and splenomegaly is found to have smudge cells on peripheral blood film. Which is the most likely diagnosis?
A case from the UKMLA question bank. The session provides the answer and explanation after your attempt.
From a decision to a learning record
- Test your reasoning. Answer five questions from this topic’s clinical-content library.
- Explore the gaps. Review explanations and use Tutor to work through decisions that need more thought.
- Reflect on application. Describe what you learned and what you would change or investigate.
- Review your evidence. Confirm the activity and time spent, then retain or export your professional record.
Primary sources and further reading
Read the source in the same jurisdiction as your question session.
- iwCLL 2018 full consensus guideline (CHIP Rigshospitalet hosted copy)International source
- Diagnosis and management of mantle cell lymphoma: A British Society for Haematology Guideline (2023; journal 2024)UK source
- Chronic lymphocytic leukemia treatment algorithm 2022 - PMC LockInternational source