NICE CKS vs iatroX (2025): Evidence Summaries vs AI-Assisted Retrieval

Last reviewed: 2025-11-04 · Reviewed by Dr Kola Tytler, MBBS CertHE MBA MRCGP

At a Glance

Who is it for?

iatroX:Individual Clinicians & Students

NICE Clinical Knowledge Summaries (CKS):All UK Primary Care Clinicians

Why choose iatroX?

  • AI-assisted natural language Q&A
  • Integrated 'Brainstorm' for case formulation
  • Integrated 'Quiz' engine for exam prep
  • Native iOS & Android apps

Why choose NICE Clinical Knowledge Summaries (CKS)?

  • The definitive 'gold standard' for UK primary care summaries
  • Directly published by NICE; universally trusted
  • Covers 370+ topics in exhaustive detail
  • Includes 'Basis for Recommendation' pages

Feature Comparison

CapabilityiatroXNICE Clinical Knowledge Summaries (CKS)
Access ModelFree for clinicians (web + apps)Open access website; no login required
Uk FocusExplicit UK focus (NICE/CKS/BNF aligned)Authoritative UK primary-care summaries
Governance M H R AUKCA-marked Class I Medical DeviceN/A (Is a guideline publisher, not a device)
Governance DataUser account required (data encrypted)Open site, no account needed
Audit TrailSession/history & CPD export availableNo personal audit trail by default
MobileNative iOS/Android apps + responsive webResponsive website
LearningAdaptive quizzes; CPD reflection & exportGuidance content (no built-in CPD logging)
Price£0 (core)£0 (open access)

In-Depth Analysis

Overview

This comparison is about synergy, not replacement. NICE CKS is the authoritative "gold standard" publisher of concise evidence summaries for UK primary care. iatroX is an AI-powered workflow tool that retrieves, synthesizes, and builds upon sources like CKS to accelerate clinical workflows.

Many clinicians use both: CKS as the definitive "library" and iatroX as the "assistant" to find and apply information from that library quickly.

When To Use Each

  • Use NICE CKS when: You need to read the full, canonical summary for a topic, understand the 'Basis for Recommendation', or require the definitive source of truth for primary care.
  • Use iatroX when: You have a specific question and need a fast, cited answer without reading a full topic page, want to practice case scenarios ('Brainstorm'), or want to test your knowledge ('Quiz').

In-Depth Comparison: Workflow & Feel

The CKS workflow is that of a traditional, highly-structured website. You use a search bar to find a topic (e.g., "Asthma") and then navigate through tabs like "Diagnosis," "Management," and "Prescribing Info." It is comprehensive and authoritative.

The iatroX workflow is interactive. You ask a natural language question (e.g., "What is the step-up plan for an adult with asthma?") and receive a direct, synthesized answer with citations back to sources like CKS and NICE.

In-Depth Comparison: Governance & Safety

NICE CKS is not a medical device; it is the guideline content itself, published by NICE and written via a rigorous editorial process. Its authority is its brand and publisher.

iatroX is a UKCA-marked Class I Medical Device. As a software tool that retrieves and presents clinical information to inform decisions, it adheres to DCB 0129 standards for clinical safety and risk management.

In-Depth Comparison: Learning & CPD

CKS is a core learning resource. Clinicians read its content to gain knowledge.

iatroX builds interactive tools on top of this knowledge. The 'Quiz' feature uses guideline content to create adaptive exam-style questions. The 'CPD' feature allows you to take a query you made (a learning activity) and write a reflection on it, which can then be exported for your portfolio.

Information based on public sources as of 4 Nov 2025. Trademarks belong to their owners.

Use-Cases

Rapid guideline look-ups

When to choose iatroX

  • Ask 'What is the first-line treatment for X?'
  • Get instant, cited summaries

When to choose NICE Clinical Knowledge Summaries (CKS)

  • Search for the 'X' topic page
  • Read the full 'Management' section

10-minute GP consults

When to choose iatroX

  • Summarised retrieval for quick decisions
  • Voice-to-text queries

When to choose NICE Clinical Knowledge Summaries (CKS)

  • Authoritative reference text for management details

Medical Student / Trainee

When to choose iatroX

  • Use 'Quiz' for UKMLA/AKT prep
  • Use 'Brainstorm' for OSCE/SCA practice

When to choose NICE Clinical Knowledge Summaries (CKS)

  • Primary reading source for topic summaries

FAQs

Does iatroX replace CKS?
No. iatroX complements CKS by accelerating retrieval and adding workflow tools. CKS is a primary source of information, while iatroX is a tool to access and interact with that information.
Is CKS free?
Yes. CKS is openly accessible online.
Can iatroX access content that isn't on CKS?
Yes. iatroX integrates a wide range of UK national guidelines, including full NICE guidelines (NG, TA, etc.), BNF, and other sources, not just the CKS summary topics.