Lexicomp vs iatroX (2025): Deep Pharmacology vs Clinical Context

Last reviewed: 2025-12-17 · Reviewed by Dr Kola Tytler, MBBS CertHE MBA MRCGP

At a Glance

Who is it for?

iatroX:Prescribers needing guideline context.

Lexicomp (UpToDate Lexidrug):Pharmacists & Specialists needing deep drug data.

Why choose iatroX?

  • **Contextual Choice**: Tells you *which* drug to pick per guidelines.
  • **Free**: No subscription needed.
  • **UK-Aligned**: Defaults to UK formulations/names.
  • **Integrated**: Links diagnosis to treatment.

Why choose Lexicomp (UpToDate Lexidrug)?

  • **Depth**: Unrivalled detail on off-label uses, mixing, and stability.
  • **Interactions**: The most robust interaction checker globally.
  • **Special Pops**: Detailed Geriatric/Pediatric/Pregnancy monographs.

Feature Comparison

CapabilityiatroXLexicomp (UpToDate Lexidrug)
Core Task-Drug Safety & Properties
Source-Independent Pharmacopoeia
Access-Paid / Institutional

In-Depth Analysis

Overview

Lexicomp is for Pharmacists. It tells you everything about the molecule—how to mix it, how it interacts, and its pharmacokinetics.

iatroX is for Prescribers. It tells you what to prescribe to follow the guideline. Use iatroX to pick the drug, and Lexicomp (or the BNF) to check the safety of that specific choice.

Use-Cases

Choosing an Antihypertensive

When to choose iatroX

  • **Recommended.** 'Start with an ACEi if under 55' (NICE).

When to choose Lexicomp (UpToDate Lexidrug)

  • Lists all antihypertensives alphabetically.

Checking IV Compatibility

When to choose iatroX

  • N/A

When to choose Lexicomp (UpToDate Lexidrug)

  • **Essential.** 'Can I mix Furosemide and Gentamicin?'

FAQs

Does iatroX replace Lexicomp?
No. For complex drug interactions or IV compatibility, Lexicomp is superior.
Is Lexicomp free?
No, it is a premium subscription, often bundled with UpToDate.