Epocrates vs UpToDate (2025): Quick Check vs Deep Dive

Last reviewed: 2025-12-19 · Reviewed by

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At a Glance

Who is it for?

Epocrates:Prescribers

UpToDate:Clinicians

Why choose Epocrates?

  • **Speed**: Instant access to dosing.
  • **Interactions**: Dedicated interaction checker.
  • **Mobile**: Designed for phone use.

Why choose UpToDate?

  • **Context**: Explains *why* to use the drug.
  • **Evidence**: Reviews the trials.
  • **Management**: Covers non-drug therapy too.

Feature Comparison

CapabilityEpocratesUpToDate
TaskPrescribingDecision Making
DepthLowHigh

In-Depth Analysis

Overview

UpToDate includes drug information (via Lexicomp), so it can do what Epocrates does. However, Epocrates is much faster if you only need the drug facts.

Looking for a faster way?

While Epocrates and UpToDate are powerful tools, iatroX offers a free, AI-driven alternative focused specifically on rapid UK guideline retrieval and exam prep.

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Use-Cases

Dose of Amoxicillin?

When to choose Epocrates

  • **Winner.** 5 seconds.

When to choose UpToDate

  • 30 seconds.

Best antibiotic for Pneumonia?

When to choose Epocrates

  • N/A

When to choose UpToDate

  • **Winner.** Explains the choice.