iatroX vs ChatGPT/Gemini for Medicine (2025): Governed Tool vs. Generalist AI

Last reviewed: 2025-11-04 · Reviewed by Dr Kola Tytler, MBBS CertHE MBA MRCGP

At a Glance

Who is it for?

iatroX:Clinicians seeking verifiable, cited **clinical answers**.

Generalist AI (ChatGPT, Gemini):Users seeking **general task assistance** (e.g., writing, summarizing).

Why choose iatroX?

  • **UKCA-marked Class I Medical Device** (governed for clinical safety)
  • Answers are **grounded in a curated UK guideline corpus** (NICE, CKS, BNF)
  • Provides **verifiable citations** to sources
  • Virtually **eliminates 'hallucinations'** on clinical facts
  • Integrated Quiz, Brainstorm, and CPD modules

Why choose Generalist AI (ChatGPT, Gemini)?

  • Incredible task flexibility (can write letters, summarize articles, code)
  • Vast general knowledge outside of medicine
  • Highly creative and conversational
  • Can process and summarize uploaded documents or web pages

Feature Comparison

CapabilityiatroXGeneralist AI (ChatGPT, Gemini)
Core FunctionClinical Decision Support (Reference)General Purpose Task Completion
Governance**UKCA-marked Class I Medical Device**N/A (Not a medical device)
Data Source**Curated UK Guidelines (NICE, CKS, BNF)**General Web Scrape (uncontrolled)
AccuracyHigh (Grounded in sources)Variable (Prone to 'hallucinations')
Citations**Yes (Direct citations to guidelines)**No (Cannot reliably cite sources)
U K Focus**UK-centric by design**US-centric or mixed bias
PriceFreeFree (with paid premium tiers)

In-Depth Analysis

Overview

This is the most important comparison: a specialist tool vs. a generalist tool.

Generalist AI (like ChatGPT, Gemini, Claude) are Large Language Models (LLMs) trained on a massive, uncontrolled scrape of the internet. They are incredibly powerful at general tasks: writing emails, summarizing text, and having human-like conversations.

iatroX is a governed, specialist tool. It is a UKCA-marked Class I Medical Device. Its AI does not use the general internet to answer clinical questions. Instead, it uses a curated, private knowledge base of UK national guidelines (NICE, CKS, BNF). This process, known as Retrieval-Augmented Generation (RAG), means its answers are grounded in trusted, verifiable sources.

When To Use Each

  • Use iatroX for: Any clinical question where accuracy, UK-specificity, and safety are critical. Use it for guideline Q&A, case brainstorming, and exam revision.
  • Use ChatGPT/Gemini for: Non-clinical tasks. Use it to help draft a patient letter, summarize a long article (that you provide), or rephrase complex ideas simply.

In-Depth Comparison: Safety & "Hallucinations"

The biggest risk of generalist AI in medicine is "hallucination"—when the AI confidently invents a fact, dose, or guideline that is plausible-sounding but dangerously incorrect.

iatroX is built to prevent this. By forcing the AI to base its answers only on the retrieved guideline documents, it virtually eliminates clinical hallucinations. Its answers are auditable and come with citations to the source material.

In-Depth Comparison: Governance & UK-Specificity

  • iatroX is a UKCA-marked medical device. It is legally registered with the MHRA and built to DCB 0129 clinical safety standards.
  • ChatGPT/Gemini are not medical devices and offer no clinical governance.

Furthermore, generalist AI has a strong US bias. Asking it about "hypertension guidelines" will likely return US (ACC/AHA) advice, which is different from the UK's (NICE) guidance. iatroX is UK-centric by design.

Public information as of 4 Nov 2025. Trademarks belong to their owners.

Use-Cases

Clinical Q&A

When to choose iatroX

  • **Recommended.** 'What is the first-line antibiotic for CAP per NICE?'

When to choose Generalist AI (ChatGPT, Gemini)

  • **High Risk.** May provide non-UK guidance or hallucinate facts.

Writing a Patient Letter

When to choose iatroX

  • N/A (Not its function)

When to choose Generalist AI (ChatGPT, Gemini)

  • **Recommended.** 'Write a simple letter explaining statins to a patient.'

UK Exam Prep

When to choose iatroX

  • **Recommended.** Use integrated, guideline-based 'Quiz' module.

When to choose Generalist AI (ChatGPT, Gemini)

  • **High Risk.** Can generate *plausible-sounding* but incorrect questions/answers.

Summarizing Research

When to choose iatroX

  • N/A

When to choose Generalist AI (ChatGPT, Gemini)

  • **Useful.** Can provide a good summary of a pasted research abstract.

FAQs

Is iatroX safer than ChatGPT for medical questions?
Yes. iatroX is a UKCA-marked medical device that grounds its answers in a curated knowledge base of UK guidelines, providing citations and preventing the 'hallucinations' common in generalist AI.
Is ChatGPT a medical device?
No. Generalist AI like ChatGPT or Gemini are not registered medical devices and are not approved for clinical decision support.
Can iatroX write patient letters or summarize articles?
No. iatroX is a specialist tool focused on its three core features: guideline Q&A, case brainstorming, and quizzes. For general administrative tasks, a generalist AI is more suitable.