Answer
Yes. Some timolol is absorbed into the bloodstream, so slow heartbeat, low blood pressure, wheezing and breathing problems can occur, although systemic reactions are less frequent than with tablets.
Sources for this answer
- Timolol 0.25% w/v Eye Drops Solution — Current selected SmPCemc · Summary of Product Characteristics
- TIOPEX timolol 1 mg/g, eye gel in single-dose container — Current selected SmPCemc · Summary of Product Characteristics