Answer
No. Swallow it whole with water because altering the tablet may affect absorption.
Sources for this answer
- Emtricitabine/Rilpivirine/Tenofovir Disoproxil Gilead 200 mg/25 mg/245 mg film coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.