Answer
Yes, especially when used therapeutically rather than as a brief diagnostic test. Possible effects include fluid retention, raised blood pressure or glucose, mood changes, infection risk, muscle weakness and bone or eye complications.
Sources for this answer
- Synacthen Depot Ampoules 1 mg/ml — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.