Answer
Yes, concurrent phenytoin and Synacthen (tetracosactide acetate) may increase the risk of liver damage, so Synacthen should be used cautiously at the minimum possible dose and for the minimum duration during concurrent treatment.
Sources for this answer
- Synacthen Ampoules 250 mcgAtnahs Pharma UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated
Sources checked