Answer
Yes. Kidney impairment is a recognised and concentration-related risk of systemic tacrolimus, which is why renal function and blood concentrations are monitored.
Sources for this answer
- Prograf 0.5mg, 1mg, 5mg Hard Capsules (UK) — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.