Answer
Omeprazole and similar acid-reducing treatments can lower sotorasib exposure. The oncology team should review the combination and provide product-specific administration instructions if it cannot be avoided.
Sources for this answer
- LUMYKRAS 240 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.