sotorasib · Medicine question

Can sotorasib be taken with omeprazole?

iatroX medicinesPublished 21 August 2026Reviewed 21 August 2026

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Omeprazole and similar acid-reducing treatments can lower sotorasib exposure. The oncology team should review the combination and provide product-specific administration instructions if it cannot be avoided.

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LUMYKRAS 240 mg film-coated tabletsemc · SmPC Current selected SmPC · Version 3

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