Answer
Kidney impairment can cause sotalol to accumulate because it is mainly cleared in urine. Prescribers must assess renal function, and the selected product is contraindicated in severe renal failure.
Sources for this answer
- Sotalol 80mg Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.