Answer
Renal impairment increases exposure because the medicine is mainly eliminated in urine. Kidney function must therefore be considered, and it is not recommended in end-stage renal disease.
Sources for this answer
- Sunosi 75 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.