Answer
Yes. Systemic sodium chloride can contribute to oedema or fluid overload, especially with heart, kidney or liver impairment or medicines that retain sodium.
Sources for this answer
- Sodium Chloride Injection BP 0.9% w/v — Current selected SmPCemc · Summary of Product Characteristics
- Sodium chloride 5mmol/ml oral solution — Current selected SmPCemc · Summary of Product Characteristics
- NHS Specialist Pharmacy Service