Answer
Yes. It can increase levodopa’s effects and worsen existing dyskinesia. Troublesome movements should be reviewed by the Parkinson’s team.
Sources for this answer
- Safinamide Amarox 100 mg — Current selected SmPCemc · Summary of Product Characteristics
- Safinamide 50 mg Film-coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.