Answer
Yes, rifampicin can reduce Cerazette (desogestrel) effectiveness through enzyme induction; use additional barrier contraception throughout concurrent treatment and for 28 days afterward, and consider an unaffected contraceptive method for long-term treatment.
Sources for this answer
- Cerazette 75 microgram film-coated tabletOrganon Pharma (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 17Document updated
Sources checked