Answer
Yes. It can prolong the QTc interval, so congenital or acquired long QT and other QT-prolonging medicines require particular caution.
Sources for this answer
- Ranolazine Aspire 375mg Prolonged-Release Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.