Answer
Kidney function affects exposure because the medicine is mainly cleared in urine. It is contraindicated for people requiring renal dialysis, and significant renal impairment requires prescriber review.
Sources for this answer
- Prucalopride 1 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.