Answer
A prescriber should review liver and kidney function. It should be avoided in severe liver impairment and end-stage kidney disease, and frequent use requires caution in severe kidney impairment.
Sources for this answer
- VYDURA 75 mg oral lyophilisate — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.