Answer
Yes, one of 94 patients (1%) in clinical studies developed IgG antibodies to velaglucerase alfa that were neutralising in an in vitro assay, while no patients developed IgE antibodies.
Sources for this answer
- VPRIV 400 Units powder for solution for infusionTakeda UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 20Document updated
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