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Medicines nivolumab + relatlimabQuestion & answer

nivolumab + relatlimab · Medicine question

Can nivolumab + relatlimab cause hepatitis?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, severe immune-related hepatitis has been observed with nivolumab + relatlimab, with signs including elevated transaminases and total bilirubin.

Sources for this answer

Opdualag 240 mg/80 mg concentrate for solution for infusionBristol Myers Squibb Pharmaceuticals limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 5Document updated 6 May 2026

Sources checked 8 November 2026

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nivolumab + relatlimab

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