Answer
Yes. Excessive cholinesterase inhibition can cause twitching followed by weakness or paralysis as part of a cholinergic crisis.
Sources for this answer
- Neostigmine Methylsulfate Injection BP 2.5mg in 1ml — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.