Answer
No. They must be swallowed whole; crushing, chewing or breaking them can release oxycodone too rapidly and cause a potentially fatal overdose.
Sources for this answer
- Targinact 5 mg/2.5 mg prolonged-release tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.