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Medicines isosorbide mononitrateQuestion & answer

isosorbide mononitrate · Medicine question

Can modified-release forms be crushed?

iatroX medicinesMedicine guide reviewed 13 August 2026

The answer

Answer

No. Crushing or chewing can interfere with controlled release. Swallow them whole unless the specific scored-tablet leaflet permits division.

Sources for this answer

Tardisc XL 60 Prolonged Release Tablets — Current selected SmPCemc · Summary of Product Characteristics
Isodur 50XL Capsules — Current selected SmPCemc · Summary of Product Characteristics
Isotard XL — Current selected SmPC

emc · Summary of Product Characteristics

General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.

The full medicine guide

isosorbide mononitrate

Read the wider context, including uses, precautions and the sources behind this medicine guide.

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