Can modified- or prolonged-release products be crushed?

iatroX medicinesPublished 19 August 2026Reviewed 19 August 2026

The answer

Answer

No. Swallow them whole because crushing or chewing can change their release.

NHSNHS · NHS medicine guidance
Tildiem LA 200mg Prolonged-Release Capsulesemc · SmPC Current selected SmPC · Version 16

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diltiazem hydrochloride · Medicine question

iatroX medicinesPublished 19 August 2026Reviewed 19 August 2026

The answer

No. Swallow them whole because crushing or chewing can change their release.

NHSNHS · NHS medicine guidance
Tildiem LA 200mg Prolonged-Release Capsulesemc · SmPC Current selected SmPC · Version 16

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