Answer
Dependence and tolerance can occur with prolonged or repeated use. Abruptly stopping an extended infusion can cause withdrawal symptoms, including seizures, so discontinuation should be clinically managed.
Sources for this answer
- Midazolam 1mg/ml, solution for injection / infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.