Answer
Usually not, because this may damage their release system. Pentasa slow-release tablets are an exception that may be broken or dispersed as described in their leaflet.
Sources for this answer
- NHSNHS · NHS medicine guidance
- Pentasa Slow Release Tablets 500mg — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.