Answer
Yes. Thrombophlebitis and pulmonary embolism are recognised adverse effects, so new leg swelling, sudden breathlessness or chest pain needs urgent assessment.
Sources for this answer
- Megace 160 mg tablet — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.