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Medicines lurasidone hydrochlorideQuestion & answer

lurasidone hydrochloride · Medicine question

Can lurasidone be taken with St John's wort?

iatroX medicinesPublished 8 November 2026

The answer

Answer

No, taking lurasidone with St John's wort (Hypericum perforatum), a strong CYP3A4 inducer, is contraindicated.

Sources for this answer

Latuda 74 mg film coated tabletsCNX Therapeutics Ltd (formerly Sunovion Pharmaceuticals Europe) · emc · SmPC §4.3 Contraindications · Version 1Document updated 13 July 2022

Sources checked 8 November 2026

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lurasidone hydrochloride

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