lorlatinib · Medicine question

Can lorlatinib impair male fertility?

iatroX medicinesPublished 8 November 2026

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Answer

Lorlatinib may impair male fertility during treatment based on non-clinical safety findings, and men should seek advice on effective fertility preservation before treatment.

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Lorviqua 25 mg film coated tablets,Pfizer Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 14Document updated 6 July 2026

Sources checked 8 November 2026

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