Answer
Yes. Phenylephrine can raise blood pressure and reduce the effect of some antihypertensive medicines; the selected product is contraindicated in hypertension.
Sources for this answer
- Nurofen Day & Night Cold & Flu 200mg/5mg Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.