Answer
Yes. Long-term metformin exposure can reduce vitamin B12, so anaemia, numbness or neuropathy may prompt testing.
Sources for this answer
- Xigduo 5 mg/1,000 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.