Answer
Yes. Skin atrophy is an uncommon reported effect, with greater risk from prolonged use, occlusion or application to sensitive skin.
Sources for this answer
- Calcipotriol/Betamethasone 50 micrograms/g + 0.5 mg/g ointment — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.