Answer
Yes. Repeated or prolonged use can cause tolerance, physical dependence and opioid use disorder, including during therapeutic use.
Sources for this answer
- Diamorphine Hydrochloride 100mg for Injection — Current selected SmPCemc · Summary of Product Characteristics
- UK GovernmentUK Government · Reputable Web
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.