Answer
No. Severe renal impairment is a contraindication because brinzolamide and its main metabolite are eliminated predominantly through the kidneys.
Sources for this answer
- Brinzolamide 10 mg/ml Eye Drops, Suspension — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.