Answer
Renal function must be assessed because impairment reduces clearance and increases bleeding risk. The selected product is contraindicated in severe renal impairment and dialysis dependence.
Sources for this answer
- Bivalirudin 250 mg Powder for solution for injection vial — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.