Answer
Kidney impairment can increase lamivudine exposure. The fixed combination may be unsuitable if individual adjustment is required, so specialist assessment is necessary.
Sources for this answer
- Lamivudine/Zidovudine Mylan 150 mg/300 mg Film-coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.