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Medicines ethambutol hydrochloride + isoniazid + pyrazinamide + rifampicinQuestion & answer

ethambutol hydrochloride + isoniazid + pyrazinamide + rifampicin · Medicine question

Can it affect the liver?

iatroX medicinesPublished 20 August 2026Reviewed 20 August 2026

The answer

Answer

Yes. Several components can cause liver injury. Jaundice, persistent sickness, weakness or poor appetite require prompt review.

Sources for this answer

Rimstar Film-coated Tablet / Voractiv Film-coated Tabletemc · SmPC Current selected SmPC · Version 11

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The full medicine guide

ethambutol hydrochloride + isoniazid + pyrazinamide + rifampicin

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