Answer
Tenofovir disoproxil can cause kidney tubular injury and reduced bone mineral density. Persistent bone pain, muscle weakness or fractures should be assessed.
Sources for this answer
- Efavirenz/Emtricitabine/Tenofovir Disoproxil Sandoz 600 mg/ 200 mg/ 245 mg film coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.