Answer
It can alter kidney function, especially with dehydration, renal artery disease, NSAIDs or other renin–angiotensin system medicines. Severe renal impairment is a contraindication.
Sources for this answer
- Olmesartan medoxomil/Hydrochlorothiazide 20 mg/12.5 mg and 20 mg/25 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.