Answer
Yes. Naproxen can reduce renal blood flow, and both components have been associated with tubulointerstitial nephritis. Risk is greater with existing kidney disease, dehydration or certain cardiovascular medicines.
Sources for this answer
- VIMOVO 500 mg/20 mg modified-release tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.