Answer
Yes, particularly with intravenous treatment, impaired renal function, excessive systemic exposure or other nephrotoxic medicines. Renal monitoring is important.
Sources for this answer
- Colomycin (Colistimethate Sodium) 1 MIU Powder for Injection, Infusion or Inhalation — Current selected SmPCemc · Summary of Product Characteristics
- Promixin 1 million International Units (IU) Powder for Nebuliser Solution — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.