Answer
Yes, particularly with intravenous treatment, impaired renal function, excessive systemic exposure or other nephrotoxic medicines. Renal monitoring is important.
Sources for this answer
- Colomycin (Colistimethate Sodium) 1 MIU Powder for Injection, Infusion or Inhalationemc · SmPC Current selected SmPC · Version 7
- Promixin 1 million International Units (IU) Powder for Nebuliser Solutionemc · SmPC Current selected SmPC · Version 15