Answer
Yes. Losartan can raise potassium, while hydrochlorothiazide can lower it. Blood tests and review of potassium supplements or salt substitutes may be needed.
Sources for this answer
- Losartan Potassium and Hydrochlorothiazide 100/12.5mg tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.