Answer
It can reduce bone mineral density and, rarely, kidney-tubule damage can cause bone softening, pain or fractures.
Sources for this answer
- Tenofovir disoproxil Dr. Reddys 245 mg Film-Coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.